Invitrogen™ EAP30 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531609

Catalog No. PIPA531609

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (98%), Rat (99%), Zebrafish (82%), Xenopus laevis (84%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.

Specifications

• Antigen: EAP30
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SNF8
• Gene Alias: D11Moh34; Dot3; Eap30; EAP30 subunit of ELL complex; ELL-associated protein of 30 kDa; ESCRT-II complex subunit VPS22; hVps22; RGD1310144; si:dkey-220f10.1; snf8; SNF8 subunit of ESCRT-II; SNF8, ESCRT-II complex subunit; SNF8, ESCRT-II complex subunit, homolog; SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae); vacuolar sorting snf8 ELL associated of 30kDa; vacuolar-sorting protein SNF8; VPS22; zgc:101578
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11267
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.68 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96H20
• Gene Symbols: SNF8
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SNF8. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov