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Invitrogen™ EB1 Polyclonal Antibody
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Catalog No. PIPA525913
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400 μL
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PIPA525913 400 μL
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Catalog No. PIPA525913 Supplier Invitrogen™ Supplier No. PA525913
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, chicken, rat and Xenopus based on sequence homology.

EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules. The MAPRE genes encode the EB1 family proteins. The human MAPRE genes MAPRE1, MAPRE2, and MAPRE3 code for EB1, RP1, and EBF3 proteins, respectively. EB1 family members appear to be expressed ubiquitously. The EB1 (MAPRE1) gene, at 20q11. 2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia. EB1 is a microtubule-associated protein that interacts with the colorectal adenomatous polyposis coli tumor-suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EB1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Mapre1
Gene Accession No. Q15691, Q61166
Gene Alias 5530600P05Rik; adenomatosis polyposis coli binding protein Eb1; adenomatous polyposis coli-binding protein EB1; AI462499; AI504412; APC-binding protein EB1; AW260097; BIM1p; D2Ertd459e; Eb1; end-binding protein 1; Mapre1; MGC117374; MGC129946; microtubule associated protein RP/EB family member 1; Microtubule-associated protein RP/EB family member 1; microtubule-associated protein RP/EB family member 1-like protein; microtubule-associated protein, RP/EB family, member 1
Gene Symbols Mapre1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 44-71 amino acids from the N-terminal region of human MAPRE1.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13589, 22919
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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