Invitrogen™ EBF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5107116

Catalog No. PIPA5107116

Description

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.

Early B-cell factor 2 (EBF2) is a gene located on chromosome 8p11.23, encoding a transcription factor involved in the regulation of gene expression during neural and adipose tissue development. EBF2 belongs to the COE family of transcription factors and plays a pivotal role in cellular differentiation processes. In the nervous system, EBF2 is essential for the development and function of neurons, particularly in regions like the olfactory system. Additionally, EBF2 is involved in adipogenesis, where it regulates genes responsible for the differentiation of brown adipocytes, contributing to thermogenesis and energy metabolism. Dysfunction or altered expression of EBF2 can impact neurological function and metabolic homeostasis, potentially influencing conditions such as obesity, diabetes, and neurodevelopmental disorders. Research into EBF2 is exploring its role in these physiological contexts and the implications of its regulatory mechanisms, offering insights into potential therapeutic approaches.

Specifications

• Antigen: EBF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EBF2
• Gene Alias: COE2; Collier, Olf and EBF 2; D14Ggc1e; early B cell factor 2; early B-cell factor 2; Ebf2; EBF-2; metencephalon-mesencephalnon-olfactory transcription factor 1; metencephalon-mesencephalon-olfactory transcription factor 1; MET-mesencephalon-olfactory TF1; MET-mesencephalon-olfactory transcription factor 1; Mmot1; O/E-3; OE-3; Olf-1/EBF-like 3; transcription factor COE2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64641
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q9HAK2
• Gene Symbols: EBF2
• Immunogen: Synthetic peptide directed towards the middle region of human EBF2 (aa 359-409).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG