EBV Early Antigens Antibody (1108-1), Alexa Fluor™ 594, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234516AF594

Catalog No. NP23416A94

Description

EBV Early Antigens Monoclonal specifically detects EBV Early Antigens in Virus samples. It is validated for Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: EBV Early Antigens
• Classification: Monoclonal
• Conjugate: Alexa Fluor 594
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Primary or Secondary: Primary
• Target Species: Virus
• Isotype: IgG1 κ

• Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: 1108-1
• Dilution: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
• Gene Alias: Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, p40, p51, p63, p73L, TP63, Transformation-related protein 63, Tumor protein 63, Tumor protein p73-like
• Immunogen: Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt′s lymphoma sera
• Quantity: 0.1 mL
• Test Specificity: Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.
• Content And Storage: Store at 4°C in the dark.