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Invitrogen™ ECD Polyclonal Antibody
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Catalog No. PIPA597685
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100 μg
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Catalog No. Quantity
PIPA597685 100 μg
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Catalog No. PIPA597685 Supplier Invitrogen™ Supplier No. PA597685
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Description

Rabbit Polyclonal Antibody

ECD Polyclonal Antibody for Western Blot, ELISA

Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen ECD
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene ECD
Gene Accession No. O95905
Gene Alias 5730461K03Rik; Ecd; ecdysoneless cell cycle regulator; ecdysoneless homolog; ecdysoneless homolog (Drosophila); GCR2; HSGT1; Human suppressor of GCR two; protein ecdysoneless homolog; protein SGT1; protein SGT1 homolog; SGT1; SGT1 protein; suppressor of GCR2; suppressor of S. cerevisiae gcr2
Gene Symbols ECD
Host Species Rabbit
Immunogen Recombinant Human Protein ecdysoneless homolog protein (1-300AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11319
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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