Invitrogen™ ECEL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5140008

Catalog No. PIPA5140008

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: LFSLTVSLDD RNSSRYVIRI DQDGLTLPER TLYLAQDEDS EKILAAYRVF MERVLSLLGA DAVEQKAQEI LQVEQQLANI TVSEHDDLR.

This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes.

Specifications

• Antigen: ECEL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ECEL1
• Gene Alias: DA5D; damage induced neuronal endopeptidase; damage-induced neuronal endopeptidase; Dine; ECEL1; ECEX; endothelin converting enzyme like 1; endothelin converting enzyme-like 1; endothelin-converting enzyme-like 1; metallopeptidase; UNQ2431/PRO4991; X converting enzyme; XCE; Xce protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9427
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95672
• Gene Symbols: ECEL1
• Immunogen: Recombinant protein corresponding to Human ECEL1. Recombinant protein control fragment (Product #RP-108557).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG