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Invitrogen™ ECM1 Monoclonal Antibody (SC-05)
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Catalog No. 01675024
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100 μg
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Catalog No. Quantity
01-675-024 100 μg
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Catalog No. 01-675-024 Supplier Invitrogen™ Supplier No. MA119051
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Description

Mouse Monoclonal Antibody

This antibody reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA). Recognized glycoprotein is specific membrane marker of glandular carcinomas.

ECM1, also referred to as extracellular matrix protein 1, is a protein that plays a significant role in regulating extracellular matrix organization and cell adhesion. It is expressed in various tissues, including the skin, lung, and liver, and is involved in the development and progression of several diseases, including cancer and dermatological disorders. The protein interacts with several extracellular matrix proteins, such as collagen and fibronectin, and is involved in the regulation of cell proliferation, migration, and invasion. ECM1 is also involved in endochondral bone formation, angiogenesis, and tumor biology. It interacts with various extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae, and certain viscera. Different isoforms of ECM1 have been described in alternatively spliced transcript variants. Diseases associated with ECM1 include Lipoid Proteinosis Of Urbach And Wiethe and Lichen Sclerosus Et Atrophicus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ECM1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone SC-05
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene ECM1
Gene Accession No. Q16610
Gene Alias AI663821; ECM1; Extracellular matrix protein 1; LOW QUALITY PROTEIN: extracellular matrix protein 1; extracellular matrix protein 1; p85; RP11-54A4.6; Secretory component p85; testicular tissue protein Li 61; URBWD
Gene Symbols ECM1
Host Species Mouse
Immunogen Affinity-purified secretory component from human colostrum.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1893
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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