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Invitrogen™ ECM1 Polyclonal Antibody
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Catalog No. PIPA5109673
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PIPA5109673 100 μL
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Catalog No. PIPA5109673 Supplier Invitrogen™ Supplier No. PA5109673
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QLRACPSHQP DISSGLELPF PPGVPTLDNI KNICHLRRFR SVPRNLPATD PLQRELLALI QLEREFQRCC RQGNNHTCTW KAWEDTLDKY CDREYAVKTH HHLCCRHPPS PTRDECFARR APYPNY.

ECM1, also referred to as extracellular matrix protein 1, is a protein that plays a significant role in regulating extracellular matrix organization and cell adhesion. It is expressed in various tissues, including the skin, lung, and liver, and is involved in the development and progression of several diseases, including cancer and dermatological disorders. The protein interacts with several extracellular matrix proteins, such as collagen and fibronectin, and is involved in the regulation of cell proliferation, migration, and invasion. ECM1 is also involved in endochondral bone formation, angiogenesis, and tumor biology. It interacts with various extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae, and certain viscera. Different isoforms of ECM1 have been described in alternatively spliced transcript variants. Diseases associated with ECM1 include Lipoid Proteinosis Of Urbach And Wiethe and Lichen Sclerosus Et Atrophicus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ECM1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.91 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ECM1
Gene Accession No. Q16610, Q61508
Gene Alias AI663821; ECM1; Extracellular matrix protein 1; LOW QUALITY PROTEIN: extracellular matrix protein 1; extracellular matrix protein 1; p85; RP11-54A4.6; Secretory component p85; testicular tissue protein Li 61; URBWD
Gene Symbols ECM1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 280-405 of human ECM1 (NP_0044162).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13601, 1893
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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