Invitrogen™ ECM1 Recombinant Rabbit Monoclonal Antibody (JE54-17)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA536164

Catalog No. PIMA536164

Description

ECM1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

ECM1, also referred to as extracellular matrix protein 1, is a protein that plays a significant role in regulating extracellular matrix organization and cell adhesion. It is expressed in various tissues, including the skin, lung, and liver, and is involved in the development and progression of several diseases, including cancer and dermatological disorders. The protein interacts with several extracellular matrix proteins, such as collagen and fibronectin, and is involved in the regulation of cell proliferation, migration, and invasion. ECM1 is also involved in endochondral bone formation, angiogenesis, and tumor biology. It interacts with various extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae, and certain viscera. Different isoforms of ECM1 have been described in alternatively spliced transcript variants. Diseases associated with ECM1 include Lipoid Proteinosis Of Urbach And Wiethe and Lichen Sclerosus Et Atrophicus.

Specifications

• Antigen: ECM1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q16610, Q62894
• Gene Symbols: ECM1
• Immunogen: Recombinant protein within Human ECM1 aa 81-232.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: JE54-17
• Conjugate: Unconjugated
• Gene: ECM1
• Gene Alias: AI663821; ECM1; Extracellular matrix protein 1; LOW QUALITY PROTEIN: extracellular matrix protein 1; extracellular matrix protein 1; p85; RP11-54A4.6; Secretory component p85; testicular tissue protein Li 61; URBWD
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 116662, 1893
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid