Invitrogen™ EDA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596219

Catalog No. PIPA596219

Description

Positive Samples: A-549, HepG2, BxPC-3, Mouse liver; Cellular Location: Cell membrane, Single-pass type II membrane protein Immunogen sequence: LELRSELRRE RGAESRLGGS GTPGTSGTLS SLGGLDPDSP ITSHLGQPSP KQQPLEPGEA ALHSDSQDGH QMALLNFFFP DEKPYSEEES RRVRRNKRSK SNEGADGPVK NKKKGKKAGP P.

EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.

Specifications

• Antigen: EDA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EDA
• Gene Alias: ECTD1; ectodermal dysplasia 1, anhidrotic; ectodermal dysplasia protein; Ectodysplasin; Ectodysplasin 1, isoform A2; ectodysplasin A; ectodysplasin-1; Ectodysplasin-A; Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form; Ed1; ED1-A1; ED1-A2; EDA; EDA 1; EDA protein; EDA protein homolog; EDA1; EDA2; Eda-A1; EDA-A2; HED; HED1; nackt; nkt; ODT1; oligodontia 1; RGD1563178; si:ch73-223d24.5; STHAGX1; Ta; tabby; Tabby protein; TNLG7C; tumor necrosis factor ligand 7C; XHED; XLHED; X-linked anhidroitic ectodermal dysplasia protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13607, 1896, 302424
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O54693, Q92838
• Gene Symbols: EDA
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 62-182 of human EDA (NP_0013901).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov