Invitrogen™ EDAR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559938

Catalog No. PIPA559938

Description

Immunogen sequence: TKDEDYGCVP CPAEKFSKGG YQICRRHKDC EGFFRATVLT PGDMENDAEC GPCLPGYYML ENRPRNIYGM VCYSCLLAPP NTKECVGATS GASANFPGTS Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Specifications

• Antigen: EDAR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Edar
• Gene Alias: Anhidrotic ectodysplasin receptor 1; DL; Downless; downless homolog; downless, mouse, homolog of; ECTD10A; ECTD10B; ectodermal dysplasia receptor; ectodysplasin 1, anhidrotic receptor; ectodysplasin A receptor; ectodysplasin-A receptor; ED1R; ED3; ED5; EDA1R; EDA3; EDA-A1 receptor; EDA-A1R; Edar; HRM1; RGD1561714; Tumor necrosis factor receptor superfamily member EDAR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10913
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.06 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UNE0
• Gene Symbols: Edar
• Immunogen: Recombinant protein corresponding to Human EDAR. Recombinant protein control fragment (Product #RP-90259).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG