Invitrogen™ EDAR Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547160

Catalog No. PIPA547160

Description

In Western blots, less than 1% cross-reactivity with recombinant human (rh) 4-1BB, rhCD27, rhCD30, rhCD40, rhDR6, rhTAJ, rhTNF RI, rhTNF RII, rhFas, rhGITR, rhHVEM, rhLTR beta, rhNGFR, rhOPG and rhRANK is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Specifications

• Antigen: EDAR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Edar
• Gene Alias: Anhidrotic ectodysplasin receptor 1; DL; Downless; downless homolog; downless, mouse, homolog of; ECTD10A; ECTD10B; ectodermal dysplasia receptor; ectodysplasin 1, anhidrotic receptor; ectodysplasin A receptor; ectodysplasin-A receptor; ED1R; ED3; ED5; EDA1R; EDA3; EDA-A1 receptor; EDA-A1R; Edar; HRM1; RGD1561714; Tumor necrosis factor receptor superfamily member EDAR
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10913
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9UNE0
• Gene Symbols: Edar
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human EDAR Glu27-Ile189.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov