Invitrogen™ EDB-FN Chimeric Recombinant Rabbit Monoclonal Antibody (A2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA548023

Catalog No. PIMA548023

Description

Specificity: This antibody bind to human Extra-Domain containing fibronectin.

EDB-FN is a variant of the fibronectin protein that contains an extra domain, known as the extra domain B. This extra domain is not present in the normal fibronectin protein and has been found to be expressed in certain tissues during embryonic development and in tumors. The extra domain has been implicated in cell adhesion, migration, and invasion, and has been shown to play a role in the progression and metastasis of certain cancers. Due to its unique expression pattern and functional properties, EDB-FN has been investigated as a potential target for cancer therapy and imaging.

Specifications

• Antigen: EDB-FN Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P02751
• Gene Symbols: FN1
• Immunogen: 2D-PAGE gel isolated human Extra-Domain containing fibronectin from lysate of human melanoma COLO-38 cells.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ

• Applications: ELISA, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Clone: A2
• Conjugate: Unconjugated
• Gene: FN1
• Gene Alias: extra domain B; extra domain B of fibronectin
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 2335
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid