Invitrogen™ EDC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522395

Catalog No. PIPA522395

Description

Recommended positive controls: A431, NIH-3T3, C2C12. Predicted reactivity: Mouse (95%), Xenopus laevis (82%), Chicken (92%), Rhesus Monkey (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.

Specifications

• Antigen: EDC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Edc3
• Gene Alias: AA517853; EDC3; enhancer of mRNA decapping 3; enhancer of mRNA decapping 3 homolog; enhancer of mRNA decapping 3 homolog (S. cerevisiae); enhancer of mRNA-decapping protein 3; hYjeF_N2; hYjeF_N2-15q23; hypothetical protein FLJ21128; hypothetical protein LOC504054; im:7151288; Lsm16; LSM16 homolog; LSM16 homolog (EDC3, S. cerevisiae); LSM16 protein homolog; MRT50; PP844; RGD1306898; wu:fb82d07; Yjdc; yjeF domain containing; yjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; yjeF_N2; YJEFN2; zgc:112006
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 353190, 80153
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8K2D3, Q96F86
• Gene Symbols: Edc3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Edc3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov