Invitrogen™ EDEM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103830

Catalog No. PIPA5103830

Description

Antibody detects endogenous levels of total EDEM1.

EDEM1 belongs to the glycosyl hydrolase 47 family. It extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner.

Specifications

• Antigen: EDEM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EDEM1
• Gene Alias: A130059K23Rik; EDEM; EDEM1; ER degradation enhancer, mannosidase alpha-like 1; ER degradation enhancing alpha-mannosidase like protein 1; ER degradation ER degradation enhancer, mannosidase alpha-like 1; ER degradation-enhancing alpha-mannosidase-like 1; ER degradation-enhancing alpha-mannosidase-like protein 1; KIAA0212; mKIAA0212; RGD1563633
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 192193, 9695
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q925U4, Q92611
• Gene Symbols: EDEM1
• Immunogen: A synthesized peptide derived from human EDEM1(Accession Q92611), corresponding to amino acid residues K610-I657.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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