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Invitrogen™ EDG3 Polyclonal Antibody
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Catalog No. PIPA533494
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50 μg
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PIPA533494 50 μg
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Catalog No. PIPA533494 Supplier Invitrogen™ Supplier No. PA533494
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%) Marmoset, Elephant (94%) Bovine (89%) Gibbon, Rabbit (83%).

EDG-3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-3 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-3 is expressed in cardiovascular, leukocyte-containing and other tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EDG3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene S1PR3
Gene Accession No. Q99500
Gene Alias AI132464; cardiac sphingosine-1-phosphate specific receptor; EDG3; EDG-3; Edg3l; Endothelial differentiation G-protein coupled receptor 3; endothelial differentiation sphingolipid G-protein-coupled receptor 3; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; FLJ37523; FLJ93220; G protein-coupled receptor, endothelial differentiation gene-3; Lpb3; Lysophospholipid receptor B3; MGC71696; S1P receptor 3; S1P receptor EDG3; S1P receptor Edg-3; S1P receptor S1P3; S1p3; S1PR3; sphingosine; Sphingosine 1-phosphate receptor 3; sphingosine 1-phosphate receptor Edg-3; sphingosine-1-phosphate receptor 3
Gene Symbols S1PR3
Host Species Rabbit
Immunogen Synthetic 18 amino acid peptide from C-terminus of human EDG3 / S1P3.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1903
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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