Invitrogen™ EDG4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554038

Catalog No. PIPA554038

Description

Immunogen sequence: LLLDGLGCES CNVLAVEKYF LLLAEANSLV NAAVYSCRDA EMRRTFRRLL CCACLRQSTR ESVHYTSSAQ GGASTRIMLP ENGHPLMDST L Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.

Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.

Specifications

• Antigen: EDG4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LPAR2
• Gene Alias: Edg4; EDG-4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; G protein-coupled receptor; IPA2; LPA receptor 2; LPA receptor EDG4; LPA2; LPA-2; LPA2 Receptor; LPAR2; Lysophosphatidic acid receptor 2; lysophosphatidic acid receptor EDG4; lysophosphatidic acid receptor Edg-4; Pbx4; pre-B-cell leukemia transcription factor 4; RGD1561336
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HBW0
• Gene Symbols: LPAR2
• Immunogen: Recombinant protein corresponding to Human EDG4. Recombinant protein control fragment (Product #RP-90853).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG