Invitrogen™ EDG4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575349

Catalog No. PIPA575349

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.

Specifications

• Antigen: EDG4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LPAR2
• Gene Alias: Edg4; EDG-4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; G protein-coupled receptor; IPA2; LPA receptor 2; LPA receptor EDG4; LPA2; LPA-2; LPA2 Receptor; LPAR2; Lysophosphatidic acid receptor 2; lysophosphatidic acid receptor EDG4; lysophosphatidic acid receptor Edg-4; Pbx4; pre-B-cell leukemia transcription factor 4; RGD1561336
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 498609, 53978, 9170
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HBW0, Q9JL06
• Gene Symbols: LPAR2
• Immunogen: Synthetic peptide corresponding to amino acids 278-325 of Human EDG4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov