Invitrogen™ EDG8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100934

Catalog No. PIPA5100934

Description

Antibody detects endogenous levels of total EDG8.

The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.

Specifications

• Antigen: EDG8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: S1PR5
• Gene Alias: Edg8; Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; lpB4; Lysophospholipid receptor B4; nerve growth factor-regulated G-protein-coupled receptor 1; Nrg1; NRG-1; S1P receptor 5; S1P receptor Edg-8; S1P(5) receptor; S1P5; S1PR5; Sphingosine 1-phosphate receptor 5; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; sphingosine-1-phosphate receptor 5; sphingosine-1-phosphate receptor LPB4; SPPR-1; SPPR-2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 53637, 94226
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q91X56, Q9H228
• Gene Symbols: S1PR5
• Immunogen: A synthesized peptide derived from human S1PR5(Accession Q9H228), corresponding to amino acid residues A341-L391.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov