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Invitrogen™ EEF2K Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA517720

Catalog No. PIPA517720


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Description

Description

It is not recommended to aliquot this antibody.

EEF2K is a highly conserved Serine/Threoning kinase in the calmodulin signaling pathway whose activity is increased in cancers including breast cancer. EEF2K (eukaryotic elongation factor 2 kinase) is a threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Up activation, by a variety of upstream kinases including AMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a single site. Then, EEF2K renders EEF2 unable to bind ribosomes and inactive - in turn, the rate of protein synthesis is reduced.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

EEF2K
Polyclonal
0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
O00418, P70531
EEF2K
Synthetic peptide corresponding to residues surrounding the N-terminus of human eEF2k.
100 μL
Primary
Human, Rat, Monkey
Antibody
IgG
Immunoprecipitation, Western Blot, Immunocytochemistry
Unconjugated
EEF2K
C86191; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; Eef2k; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; kinase eEF2K; SMEF2K
Rabbit
Antigen affinity chromatography
RUO
25435, 29904
-20°C
Liquid
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