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Invitrogen™ EEF2K Polyclonal Antibody
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Catalog No. PIPA517720
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100 μL
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Catalog No. Quantity
PIPA517720 100 μL
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Catalog No. PIPA517720 Supplier Invitrogen™ Supplier No. PA517720
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Description

Rabbit Polyclonal Antibody

It is not recommended to aliquot this antibody.

EEF2K is a highly conserved Serine/Threoning kinase in the calmodulin signaling pathway whose activity is increased in cancers including breast cancer. EEF2K (eukaryotic elongation factor 2 kinase) is a threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Up activation, by a variety of upstream kinases including AMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a single site. Then, EEF2K renders EEF2 unable to bind ribosomes and inactive - in turn, the rate of protein synthesis is reduced.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EEF2K
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene EEF2K
Gene Accession No. O00418, P70531
Gene Alias C86191; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; Eef2k; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; kinase eEF2K; SMEF2K
Gene Symbols EEF2K
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues surrounding the N-terminus of human eEF2k.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25435, 29904
Target Species Human, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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