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Invitrogen™ EEF2K Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA517720
Description
It is not recommended to aliquot this antibody.
EEF2K is a highly conserved Serine/Threoning kinase in the calmodulin signaling pathway whose activity is increased in cancers including breast cancer. EEF2K (eukaryotic elongation factor 2 kinase) is a threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Up activation, by a variety of upstream kinases including AMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a single site. Then, EEF2K renders EEF2 unable to bind ribosomes and inactive - in turn, the rate of protein synthesis is reduced.
Specifications
EEF2K | |
Polyclonal | |
0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
O00418, P70531 | |
EEF2K | |
Synthetic peptide corresponding to residues surrounding the N-terminus of human eEF2k. | |
100 μL | |
Primary | |
Human, Rat, Monkey | |
Antibody | |
IgG |
Immunoprecipitation, Western Blot, Immunocytochemistry | |
Unconjugated | |
EEF2K | |
C86191; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; Eef2k; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; kinase eEF2K; SMEF2K | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
25435, 29904 | |
-20°C | |
Liquid |
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