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Invitrogen™ EEF2K Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA584276
Description
Immunogen sequence: GFDYLLKAAE AGDRQSMILV ARAFDSGQNL SPDRCQDWLE ALHWYNTALE MTDCDEGGEY DGMQDEPRYM MLAREAEMLF TG.
EEF2K is a highly conserved Serine/Threoning kinase in the calmodulin signaling pathway whose activity is increased in cancers including breast cancer. EEF2K (eukaryotic elongation factor 2 kinase) is a threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Up activation, by a variety of upstream kinases including AMPK or TRPM7, EEF2K phosphorylates the elongation factor EEF2 at a single site. Then, EEF2K renders EEF2 unable to bind ribosomes and inactive - in turn, the rate of protein synthesis is reduced.
Specifications
EEF2K | |
Polyclonal | |
Unconjugated | |
EEF2K | |
C86191; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase; calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase; calmodulin-dependent protein kinase III; EC 2.7.11.20; eEF-2 kinase; Eef2k; eEF-2K; EF2K; elongation factor 2 kinase; elongation factor-2 kinase; euk; eukaroytic elongation factor 2 kinase; eukaryotic elongation factor 2 kinase; eukaryotic elongation factor-2 kinase; HSU93850; kinase eEF2K; SMEF2K | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
29904 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunofluorescence | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O00418 | |
EEF2K | |
Recombinant protein corresponding to Human EEF2K. Recombinant protein control fragment (Product #RP-106680). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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