Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 392210

Tocris Bioscience™ Eeyarestatin I
GREENER_CHOICE

Catalog No. 392210
Change view
Click to view available options
Quantity:
10 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
39-2210 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 39-2210 Supplier Tocris Bioscience™ Supplier No. 3922/10
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Potent inhibitor of ER-associated protein degradation and translocation

Eeyarestatin I is a potent inhibitor of endoplasmic reticulum associated protein degradation (ERAD). Specifically targets the p97-associated deubiquitinating process (PAD) and inhibits ataxin-3 (atx3)-dependent deubiquitination. Also inhibits Sec61-mediated protein translocation at the ER. Displays cytotoxic activity preferentially against cancer cells; induces cell death via the proapoptotic protein NOXA. Also enhances adeno-associated viral transduction in multiple cells types.

Chemical Identifiers

CAS 412960-54-4
Molecular Formula C27H25Cl2N7O7

Specifications

Quantity 10 mg
Formula Weight 630.44
Purity >98%
Chemical Name or Material Eeyarestatin I

Safety and Handling

Recommended Storage Desiccate at +4°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.