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Invitrogen™ EFCAB4A Polyclonal Antibody
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Catalog No. PIPA561187
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100 μL
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PIPA561187 100 μL
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Catalog No. PIPA561187 Supplier Invitrogen™ Supplier No. PA561187
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LEAVFESLDQ AHTGFLTARE FCLGLGMFVG VASAQGANPC RTPEETFESG GLDVQGTAGS LDEE Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.

EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EFCAB4A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CRACR2B
Gene Accession No. Q8N4Y2
Gene Alias 6330520A15Rik; BC026645; Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B; calcium release activated channel regulator 2B; calcium release-activated calcium channel regulator 2B; Calcium release-activated channel regulator 2B; CRAC channel regulator 2B; CRAC regulator 2B; Cracr2a; CRACR2B; Efcab4; EFCAB4A; EF-hand calcium binding domain 4A; EF-hand calcium-binding domain-containing protein 4A; RGD1560911
Gene Symbols CRACR2B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human EFCAB4A. Recombinant protein control fragment (Product #RP-97506).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 283229
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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