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Invitrogen™ EFHA1 Polyclonal Antibody
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Catalog No. PIPA588410
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100 μL
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PIPA588410 100 μL
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Catalog No. PIPA588410 Supplier Invitrogen™ Supplier No. PA588410
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Description

Rabbit Polyclonal Antibody

Positive Samples: 293T, Mouse skeletal muscle, Rat skeletal muscle; Cellular Location: Mitochondrion intermembrane space Immunogen sequence: TNETGYQEAI VKEPEIN.

Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EFHA1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.11 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene MICU2
Gene Accession No. Q8IYU8
Gene Alias 09C01; 1110008L20Rik; 4833427E09Rik; AU041871; Calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; EFHA1; EF-hand domain family member A1; EF-hand domain family, member A1; EF-hand domain-containing family member A1; Micu2; mitochondrial calcium uptake 2; RGD1309934; Smhs2; Smhs2 homolog
Gene Symbols MICU2
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221154
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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