EFHA1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS9011R

Catalog No. 50-198-8749

Description

Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.

Specifications

• Antigen: EFHA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MICU2
• Gene Alias: 09C01; 1110008L20Rik; 4833427E09Rik; AU041871; Calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; Efha1; EF-hand domain family member A1; EF-hand domain family, member A1; EF-hand domain-containing family member A1; MICU2; mitochondrial calcium uptake 2; RGD1309934; Smhs2; Smhs2 homolog
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 221154
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q8IYU8
• Gene Symbols: MICU2
• Immunogen: KLH conjugated synthetic peptide derived from human EFHA1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG