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EFHA1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988749
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100 μL
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50-198-8749 100 μL
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Catalog No. 50-198-8749 Supplier Bioss Supplier No. BS9011R
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Description

Rabbit Polyclonal Antibody

Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.

Specifications

Antigen EFHA1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MICU2
Gene Accession No. Q8IYU8
Gene Alias 09C01; 1110008L20Rik; 4833427E09Rik; AU041871; Calcium uptake protein 2, mitochondrial; EF hand domain family A1; EF hand domain family, member A1; Efha1; EF-hand domain family member A1; EF-hand domain family, member A1; EF-hand domain-containing family member A1; MICU2; mitochondrial calcium uptake 2; RGD1309934; Smhs2; Smhs2 homolog
Gene Symbols MICU2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human EFHA1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221154
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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