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Invitrogen™ EFHD2 Polyclonal Antibody
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Catalog No. PIPA578575
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Quantity:
100 μL
Catalog No. Quantity
PIPA578575 100 μL
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Catalog No. PIPA578575

Supplier: Invitrogen™ PA578575

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Description

Rabbit Polyclonal Antibody

Positive Control: H1299, HeLaS3, mouse brain, rat brain Predicted Reactivity: Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EFHD2
Applications Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Efhd2
Gene Accession No. Q4FZY0, Q96C19, Q9D8Y0
Gene Alias 2600015J22Rik; AA408606; D4Wsu27e; EF hand domain containing 2; EF hand domain family, member D2; EF-hand domain family member D2; EF-hand domain family, member D2; EF-hand domain-containing protein D2; Efhd2; MGC4342; RP3-467K16.3; swiprosin 1; swiprosin-1; Sws1; testicular tissue protein Li 62
Gene Symbols Efhd2
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human EFHD2. The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27984, 298609, 79180
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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