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EFHD2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501727775 Shop All Proteintech Group Inc Products
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50-172-7775 150 μL
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Catalog No. 50-172-7775 Supplier Proteintech Group Inc Supplier No. 121811AP150UL

Rabbit Polyclonal Antibody

EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLC-gamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.

Specifications

Antigen EFHD2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.18 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene EFHD2
Gene Accession No. Q96C19, Q9D8Y0
Gene Alias EFHD2, Swiprosin 1, SWS1
Gene Symbols Efhd2
Host Species Rabbit
Immunogen EFHD2 Fusion Protein Ag2826
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27984, 79180
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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