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  5. 452450

Tocris Bioscience™ EGCG
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Catalog No. 452450
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

β-secretase inhibitor; inhibits amyloid assembly

β-secretase (BACE1) inhibitor (IC50 = 1.6 μM); inhibits amyloid assembly. Inhibits the formation of amyloid fibrils by proteins such as Aβ, α-synuclein and huntingtin. Reduces Aβ42-induced cell death in three different cell types. Also inhibits glutamate dehydrogenase. Inhibits cell growth and selectively induces apoptosis in A431 and human pancreatic cancer cells. Also a DNMT1 inhibitor.

Chemical Identifiers

CAS 989-51-5
Molecular Formula C22H18O11

Specifications

Quantity 50 mg
Formula Weight 458.37
Purity >99%
Molecular Weight (g/mol) 458.375
Chemical Name or Material EGCG

Safety and Handling

Recommended Storage Store at -20°C
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