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EGF Receptor Mouse, anti-Human, R718, Clone: EMAB-134, BD OptiBuild™

Catalog No. BDB751864 Shop All BD Biosciences Products
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BDB751864 50 μg
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Catalog No. BDB751864 Supplier BD Biosciences Supplier No. 751864
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Description

Mouse Monoclonal Antibody

The EMab-134 monoclonal antibody specifically recognizes the epidermal growth factor receptor (EGF-R). The EGF-R is a transmembrane glycoprotein of approximately 170 kDa that is expressed on most cells. It consists of a glycosylated extracellular domain which binds to epidermal growth factor (EGF), a transmembrane domain, and an intracellular domain with tyrosine-kinase activity essential for signal transduction. The epitope recognized by EMab-134 is an extracellular peptide that is not affected by glycosylation. The EGF-R plays an important role in the growth and differentiation of many cellular types. Transforming growth factor α (TGFα), vaccinia virus growth factor, and related growth factors can also bind to and signal through the EGF-R.

TRUSTED_SUSTAINABILITY

Specifications

Antigen EGF Receptor
Applications Flow Cytometry
Classification Monoclonal
Clone EMAB-134
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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