Invitrogen™ EGFL6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113106

Catalog No. PIPA5113106

Description

EGFL6 Polyclonal Antibody for Western Blot, IHC (P), ELISA

The EGFL6 gene encodes epidermal growth factor-like domain-containing protein 6, a member of the EGF-like repeat superfamily known for its roles in development and angiogenesis. EGFL6 is expressed at higher levels during embryonic development and has notable expression in various malignant tumors, highlighting its potential involvement in cancer progression. This secreted protein is pivotal in promoting tumor angiogenesis, influencing cancer cell migration and proliferation without affecting wound healing, making it a significant factor in tumor growth and metastasis. EGFL6 is also expressed in adipose tissues, and its role in adipose differentiation suggests it might link obesity to endometrial cancer risks. The protein impacts cellular activities such as cell adhesion, migration, and proliferation, contributing fundamentally to tumor dynamics. Consequently, EGFL6 is considered an attractive target for antibody-based therapies, with research evaluating its utility in cancer intervention strategies.

Specifications

• Antigen: EGFL6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EGFL6
• Gene Alias: EGF like domain multiple 6; EGF repeat-containing protein 6; EGFL6; EGF-like protein 6; EGF-like-domain, multiple 6; Epidermal growth factor-like protein 6; Maeg; MAM and EGF domain containing; MAM and EGF domains-containing gene protein; PP648; Protein W80; UNQ281/PRO320; W80
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 25975
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 4 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q8IUX8
• Gene Symbols: EGFL6
• Immunogen: Recombinant Human Epidermal growth factor-like protein 6 protein (301-554AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov