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Invitrogen™ EGFL6 Polyclonal Antibody
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Catalog No. PIPA5114393
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100 μg
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Catalog No. Quantity
PIPA5114393 100 μg
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Catalog No. PIPA5114393 Supplier Invitrogen™ Supplier No. PA5114393
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human U-87MG whole cell, human A431 whole cell, human HL-60 whole cell, human K562 whole cell, human THP-1 whole cell, human Hela whole cell, rat liver tissue, mouse thymus tissue, mouse lung tissue, mouse liver tissue, mouse SP20 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The EGFL6 gene encodes epidermal growth factor-like domain-containing protein 6, a member of the EGF-like repeat superfamily known for its roles in development and angiogenesis. EGFL6 is expressed at higher levels during embryonic development and has notable expression in various malignant tumors, highlighting its potential involvement in cancer progression. This secreted protein is pivotal in promoting tumor angiogenesis, influencing cancer cell migration and proliferation without affecting wound healing, making it a significant factor in tumor growth and metastasis. EGFL6 is also expressed in adipose tissues, and its role in adipose differentiation suggests it might link obesity to endometrial cancer risks. The protein impacts cellular activities such as cell adhesion, migration, and proliferation, contributing fundamentally to tumor dynamics. Consequently, EGFL6 is considered an attractive target for antibody-based therapies, with research evaluating its utility in cancer intervention strategies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EGFL6
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene EGFL6
Gene Accession No. Q8IUX8, Q9JJZ5
Gene Alias EGF like domain multiple 6; EGF repeat-containing protein 6; EGFL6; EGF-like protein 6; EGF-like-domain, multiple 6; Epidermal growth factor-like protein 6; Maeg; MAM and EGF domain containing; MAM and EGF domains-containing gene protein; PP648; Protein W80; UNQ281/PRO320; W80
Gene Symbols EGFL6
Host Species Rabbit
Immunogen E.coli-derived human EGFL6 recombinant protein (Position: K354-D535).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25975, 317470, 54156
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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