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EGFR Antibody (GFR450), Novus Biologicals™
SDP

Catalog No. NBP229440 Shop All R&D Systems Products
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NBP229440 0.1 mg
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Catalog No. NBP229440 Supplier Novus Biologicals Supplier No. NBP229440
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Description

Mouse Monoclonal Antibody

EGFR Monoclonal specifically detects EGFR in Human, Mouse (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array, Immunofluorescence.

Specifications

Antigen EGFR
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array, Immunofluorescence
Classification Monoclonal
Clone GFR450
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1 μg/million cells in 0.1 mL, Immunohistochemistry, Immunohistochemistry-Paraffin 0.5-1.0 μg/mL, Protein Array, Immunofluorescence 1-2 μg/mL
Gene Accession No. P00533
Gene Alias avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Gene Symbols EGFR
Host Species Mouse
Immunogen Recombinant extracellular domain of human EGFR protein (Uniprot: P00533)
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 1956
Test Specificity This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Target Species Human, Mouse (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a κ
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