EGFR Antibody (GFR450), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP229440

Catalog No. NBP229440

Description

EGFR Monoclonal specifically detects EGFR in Human, Mouse (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array, Immunofluorescence.

Specifications

• Antigen: EGFR
• Classification: Monoclonal
• Concentration: 0.2 mg/ml
• Dilution: Flow Cytometry 0.5-1 μg/million cells in 0.1 mL, Immunohistochemistry, Immunohistochemistry-Paraffin 0.5-1.0 μg/mL, Protein Array, Immunofluorescence 1-2 μg/mL
• Gene Alias: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
• Content And Storage: Store at 4C.
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array, Immunofluorescence
• Clone: GFR450
• Conjugate: Unconjugated
• Gene Accession No.: P00533
• Gene Symbols: EGFR
• Immunogen: Recombinant extracellular domain of human EGFR protein (Uniprot: P00533)
• Quantity: 0.1 mg
• Research Discipline: Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
• Gene ID (Entrez): 1956
• Target Species: Human, Mouse (Negative)
• Form: Purified

For Research Use Only