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EGFR Mouse anti-Human, Clone: SPM622, Abnova™

Catalog No. 89934072 Shop All Abnova Corporation Products
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89-934-072 100 μg
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Catalog No. 89-934-072 Supplier Abnova Corporation Supplier No. MAB13063
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Mouse monoclonal antibody raised against native human EGFR.

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq]

Specifications

Antigen EGFR
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone SPM622
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native human EGFR.
Dilution Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS.
Gene Alias ERBB/ERBB1/HER1/PIG61/mENA
Gene Symbols EGFR
Host Species Mouse
Immunogen Native purified EGFR from human A431 cells.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1956
Target Species Human
Content And Storage Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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