EGFRvIII mutation Mouse anti-Human, Unconjugated, Clone: L8A4, MilliporeSigma™

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma MABC1126100UG

Catalog No. MABC1126-100

Description

Anti-EGFRvIII mutation, clone L8A4, Cat. No. MABC1126, is a mouse monoclonal antibody that detects Epidermal Growth Factor Receptor variant III and has been tested for use in ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), and Western Blotting.

Specifications

• Antigen: EGFRvIII mutation
• Classification: Monoclonal
• Concentration: Please refer to lot specific datasheet.
• Formulation: Purified mouse monoclonal antibody IgG1 in PBS without azide.
• Gene Symbols: EGFR;ERBB;ERBB1;HER1
• Immunogen: KLH-conjugated linear peptide corresponding to the predicted amino acid sequence of 14 amino acids at the fusion junction combined with cultured HC2 20 d2 cells.
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Clone L8A4 specifically binds to EGFRvIII, a mutated form of EGFR.
• Content And Storage: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
• Form: Purified

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: L8A4
• Conjugate: Unconjugated
• Gene Alias: Epidermal Growth Factor Receptor vIII
• Host Species: Mouse
• Molecular Weight of Antigen: ∽145 kDa observed. Uncharacterized bands may be observed in some lysate(s).
• Quantity: 100 μg
• Research Discipline: Apoptosis & Cancer
• Gene ID (Entrez): NP_005219
• Target Species: Human
• Product Type: Antibodies
• Isotype: IgG1 κ