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Invitrogen™ EGR2 Polyclonal Antibody
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Catalog No. PIPA579191
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PIPA579191 100 μg
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Catalog No. PIPA579191 Supplier Invitrogen™ Supplier No. PA579191
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Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: NIH3T3 Cell, MCF-7 Cell.

The EGR2 gene provides instructions for making a protein called early growth response 2, which is part of the early growth response family of proteins. These proteins bind to specific areas of DNA and help control the activity of particular genes. On the basis of this action, the proteins are referred to as transcription factors. The early growth response 2 protein activates several genes that are involved in the formation and maintenance of myelin, the fatty substance that covers and protects nerve cells. Myelin promotes the efficient transmission of nerve impulses. If myelin is lost (demyelination) or its structure is disrupted, the transmission of nerve impulses is impaired. Mutations in the EGR2 gene can cause two forms of Charcot-Marie-Tooth disease, type 1D or type 4E (sometimes called congenital hypomyelinating neuropathy) or a severe form of type 1D (sometimes called Dejerine-Sottas syndrome) that begins during infancy or early childhood.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EGR2
Applications Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene Egr2
Gene Accession No. P08152, P11161, P51774
Gene Alias AT591; CMT1D; CMT4E; DKFZp686J1957; E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; early growth response 2; early growth response protein 2; Egr2; Egr-2; FLJ1454; FLJ14547; Krox20; Krox-20; Krox-20 homolog; KROX-20, Drosophila, homolog (early growth response-2); NGF1-B; OTTHUMP00000062133; Zfp-25; Zfp-6; Zinc finger protein Krox-20
Gene Symbols Egr2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human EGR2 (153-168aa TMSQTQPDLDHLYSPP).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114090, 13654, 1959
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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