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Invitrogen™ EHD1 Polyclonal Antibody
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Catalog No. PIPA5102954
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100 μL
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PIPA5102954 100 μL
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Catalog No. PIPA5102954 Supplier Invitrogen™ Supplier No. PA5102954
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total EHD1.

EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. EHD1 also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Further, EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The EHD1 protein is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EHD1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EHD1
Gene Accession No. Q641Z6, Q9H4M9, Q9WVK4
Gene Alias AA409636; CDABP0131; EH domain containing 1; EH domain-containing protein 1; Ehd1; EH-domain containing 1; H-PAST; HPAST1; mPAST1; PAST; PAST homolog 1; PAST1; RGD1306960; RME-1; testilin
Gene Symbols EHD1
Host Species Rabbit
Immunogen A synthesized peptide derived from human EHD1(Accession Q9H4M9), corresponding to amino acid residues F422-V472.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10938, 13660, 293692
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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