Invitrogen™ EHD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102954

Catalog No. PIPA5102954

Description

Antibody detects endogenous levels of total EHD1.

EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. EHD1 also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Further, EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The EHD1 protein is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.

Specifications

• Antigen: EHD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EHD1
• Gene Alias: AA409636; CDABP0131; EH domain containing 1; EH domain-containing protein 1; Ehd1; EH-domain containing 1; H-PAST; HPAST1; mPAST1; PAST; PAST homolog 1; PAST1; RGD1306960; RME-1; testilin
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10938, 13660, 293692
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q641Z6, Q9H4M9, Q9WVK4
• Gene Symbols: EHD1
• Immunogen: A synthesized peptide derived from human EHD1(Accession Q9H4M9), corresponding to amino acid residues F422-V472.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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