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Invitrogen™ EHD1 Recombinant Rabbit Monoclonal Antibody (5S4P9)
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Catalog No. PIMA542814
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PIMA542814 100 μL
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Catalog No. PIMA542814 Supplier Invitrogen™ Supplier No. MA542814
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HeLa, THP-1, U-251MG, Mouse liver, Mouse brain, Mouse spleen, Rat lung, Rat testis, Rat kidney. The target is usually found in the following locations: Cell membrane, Cell projection, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein, Recycling endosome membrane, cilium membrane. Immunogen sequence: MFSWVSKDAR RKKEPELFQT VAEGLRQLYA QKLLPLEEHY RFHEFHSPAL EDADFDNKPM VLLVGQYSTG KTTFIRHLIE QDFPGMRIGP EPTTDSFIAV.

EHD1 acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. EHD1 also plays a role in myoblast fusion and is recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Further, EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The EHD1 protein is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for the EHD1 gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EHD1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 5S4P9
Concentration 1.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EHD1
Gene Accession No. Q641Z6, Q9H4M9, Q9WVK4
Gene Alias AA409636; CDABP0131; EH domain containing 1; EH domain-containing protein 1; Ehd1; EH-domain containing 1; H-PAST; HPAST1; mPAST1; PAST; PAST homolog 1; PAST1; RGD1306960; RME-1; testilin
Gene Symbols EHD1
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10938, 13660, 293692
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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