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Invitrogen™ EHD3 Polyclonal Antibody
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Catalog No. PIPA5100497
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PIPA5100497 100 μL
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Catalog No. PIPA5100497 Supplier Invitrogen™ Supplier No. PA5100497
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total EHD2.

The EHD3 gene encodes the EH-domain containing protein 3, part of the EHD protein family involved in the regulation of endocytic recycling and membrane trafficking. EHD3 plays a crucial role in the endosomal transport system, impacting how receptors and other membrane proteins are recycled back to the cell surface after internalization. This protein aids in maintaining cellular homeostasis by ensuring the efficient sorting and transport of cargo through the endosomal system. EHD3 has been implicated in various cellular functions, including insulin signaling, receptor recycling, and neuronal development, and significantly influences synaptic transmission and plasticity. Alterations in EHD3 expression or function can disrupt endosomal trafficking processes and are linked to conditions such as neurodegenerative diseases and cancer. Research on EHD3 is focused on uncovering its role in membrane dynamics and identifying potential therapeutic strategies for disorders involving dysfunctional endocytic pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EHD3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EHD3
Gene Accession No. Q8R491, Q9NZN3, Q9QXY6
Gene Alias EH domain containing 3; EH domain-containing protein 3; Ehd2; Ehd3; EH-domain containing 3; EH-domain containing protein 2; PAST homolog 3; PAST3; si:ch211-147c1.2
Gene Symbols EHD3
Host Species Rabbit
Immunogen A synthesized peptide derived from human EHD3(Accession Q9NZN3), corresponding to amino acid residues N334-D384.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192249, 30845, 57440
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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