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EHHADH Polyclonal Antibody, Invitrogen™

Catalog No. PIPA589260
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PIPA589260 100 μL
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Catalog No. PIPA589260 Supplier Thermo Scientific Supplier No. PA589260

Description

Rabbit Polyclonal Antibody

Immunogen sequence: EVIPSQYSSP TTIATVMNLS KKIKKIGVVV GNCFGFVGNR MLNPYYNQAY FLLEEGSKPE EVDQVLEEFG FKMGPFRVSD LAGLDVGWKS RKGQGLTGPT LLPGTPARKR GNRRYCPIPD VLCELGRFGQ KTGKGWYQYD KPLGRIHKPD PWLSKFLSRY RKTHHIEPRT ISQDEILERC LYSLINEAFR ILGEGIAASP EHIDVVYLHG YGWPRHKGGP MFYASTVGLP TVLEKLQKYY RQNPDIPQLE PSDYLKKLAS QGNPPLKEWQ SLAGSPSSKL; Positive Samples: HepG2, Mouse liver, Rat liver, Rat kidney; Cellular Location: Peroxisome

As an L-hydroxy-specific enzyme, EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein has an essential tripeptide sequence on its carboxyl-terminus that is required for peroxisomal transport. EHHADH-null mice only exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there were no observed changes in lipid metabolism, this evidence suggests that enoyl-CoAs were diverted to the D-hydroxy-specific beta-oxidation system for metabolism.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EHHADH
Applications Immunocytochemistry, Western Blot, Western Blot
Classification Polyclonal
Concentration 0.94 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene EHHADH
Gene Accession No. P07896, Q08426, Q9DBM2
Gene Alias 1, 1300002P22Rik, 3,2-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, ECHD, EHHADH, Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase, enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase, enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase, FRTS3, HD, L-3-hydroxyacyl-CoA dehydrogenase, LBFP, L-bifunctional enzyme, L-bifunctional protein, peroxisomal, Lbp, L-PBE, L-specific bifunctional protein, L-specific multifunctional beta-oxdiation protein, MEF, Mfe, Mfe1, MFP, MFP1, multifunctional enzyme type 1, Pbe, PBFE, perMFE-1, Peroxisomal bifunctional enzyme, peroxisomal bifunctional enzyme type 1, peroxisomal enoyl-CoA hydratase
Gene Symbols EHHADH
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 444-723 of human EHHADH (NP_0019572)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171142, 1962, 74147
Target Species Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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