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Tocris Bioscience™ EHop 016

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Quantity:
5 mg
25 mg
Description
EHop 016 is a Rac inhibitor (IC50 = 1.1 μM). Exhibits some selectivity for Rac1 and Rac3 over Cdc42. Blocks the interaction of Rac with guanine nucleotide exchange factor Vav2 in breast cancer cell lines expressing high levels of Rac activity and inhibits activity of Rac downstream effector PAK1. Also inhibits mammary tumor growth and metastasis in mice.
Specifications
Specifications
Chemical Name or Material | Rho GTPase Inhibitors |
CAS | 1380432-32-5 |
Assay Percent Range | >98% |
Quantity | 25 mg |
Molecular Formula | C25H30N6O |
Formula Weight | Observed MW: 430.55 |
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