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  5. Tocris Bioscience™ EHop 016

Tocris Bioscience™ EHop 016
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Catalog No. 624825
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Rac inhibitor

EHop 016 is a Rac inhibitor (IC50 = 1.1 μM). Exhibits some selectivity for Rac1 and Rac3 over Cdc42. Blocks the interaction of Rac with guanine nucleotide exchange factor Vav2 in breast cancer cell lines expressing high levels of Rac activity and inhibits activity of Rac downstream effector PAK1. Also inhibits mammary tumor growth and metastasis in mice.

Specifications

Chemical Name or Material Rho GTPase Inhibitors
CAS 1380432-32-5
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C25H30N6O
Formula Weight Observed MW: 430.55
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