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EID1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 117341AP150UL

Encompass_Preferred

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Catalog No. 50-172-7413


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Description

Description

E1A-like inhibitor of differentiation-1 (EID-1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. EID-1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID-1 also acetylates both histones and non-histone proteins such as NCOA3 co-activator. By acetylating histones, EID-1 gives a specific tag for transcriptional activation. In addition to binding Rb and p300, EID-1 also binds to phosphorylated CREB protein, mediating cAMP gene regulation. EID-1 augments the activity of phosphorylated CREB and activates transcription of cAMP responsive genes as a co-activator.
Specifications

Specifications

EID1
Polyclonal
Unconjugated
EID1
21 kDa pRb associated protein, C15orf3, CRI1, EID 1, EID1, IRO45620, PNAS 22, PTD014, RBP21
Rabbit
Antigen Affinity Chromatography
RUO
23741, 58521
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9DCR4, Q9Y6B2
Eid1
EID1 Fusion Protein Ag2336
150 μL
Primary
Human, Mouse
Antibody
IgG
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