Invitrogen™ eIF2 beta Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528469

Catalog No. PIPA528469

Description

Recommended positive controls: 293T, A431, H1299, HeLa, mouse liver, PC-12, Rat2. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Xenopus laevis (98%), Rabbit (100%), Chicken (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: eIF2 beta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EIF2S2
• Gene Alias: 2810026E11Rik; 38kDa; AA408636; AA571381; AA986487; AW822225; D2Ertd303e; EIF2; EIF2B; EIF2BA; EIF2beta; eIF-2-beta; EIF2S2; Eukaryotic translation initiation factor 2 subunit 2; eukaryotic translation initiation factor 2 subunit beta; eukaryotic translation initiation factor 2, subunit 2 (beta); eukaryotic translation initiation factor 2, subunit 2 (beta, 38kDa); eukaryotic translation initiation factor 2, subunit 2 beta; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; PPP1R67; protein phosphatase 1, regulatory subunit 67
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 296302, 67204, 8894
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P20042, Q99L45
• Gene Symbols: EIF2S2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF2 beta. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov