EIF2S1 Mouse anti-Human, Clone: AT5E10, Abnova™

Catalog No.	Quantity
89-934-076	50 μL

Catalog No. 89-934-076 Supplier Abnova Corporation Supplier No. MAB12654

Description

Mouse monoclonal antibody raised against human EIF2S1.

The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM]

Specifications

• Antigen: EIF2S1
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: AT5E10
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against human EIF2S1.
• Dilution: ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide).
• Gene Alias: EIF-2/EIF-2A/EIF-2alpha/EIF2/EIF2A
• Gene Symbols: EIF2S1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human EIF2S1.
• Purification Method: Protein G purification
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1965
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b κ