Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA527527

Invitrogen™ eIF3c Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA527527
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA527527 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA527527 Supplier Invitrogen™ Supplier No. PA527527
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (93%), Xenopus laevis (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF3c
Applications Western Blot
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Eif3c
Gene Accession No. Q99613
Gene Alias 110kDa; 3230401O13Rik; cell migration-inducing protein 17; eIF3 p110; eIF3 p110 {ECO:0000255; eIF3c; eIF3c {ECO:0000255; EIF3CL; eIF3-p110; EIF3S8; eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3 subunit 8 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit C; eukaryotic translation initiation factor 3 subunit C {ECO:0000255; eukaryotic translation initiation factor 3, subunit 8 (110 kDa); eukaryotic translation initiation factor 3, subunit 8 (110kD); eukaryotic translation initiation factor 3, subunit 8, 110kDa; eukaryotic translation initiation factor 3, subunit C; extra-toes spotting; HAMAP-Rule:MF_03002}; NIPIL(A3); NipilA3; NIPI-like protein; Xs; Xsl
Gene Symbols Eif3c
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human EIF3S8. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8663
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.