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Invitrogen™ eIF3g Polyclonal Antibody
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Catalog No. PIPA523287
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100 μg
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PIPA523287 100 μg
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Catalog No. PIPA523287 Supplier Invitrogen™ Supplier No. PA523287
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Description

Rabbit Polyclonal Antibody

The amino acid sequence used as immunogen is 84% homologous in mouse.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF3g
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene EIF3G
Gene Accession No. O75821
Gene Alias 44kDa; D0Jmb4; eiF3 delta; eIF3 p42; eIF3 p42 {ECO:0000255; eIF3 p44; eIF3 p44 {ECO:0000255; eIF-3 RNA-binding subunit; eIF-3 RNA-binding subunit {ECO:0000255; eIF-3-delta; eIF3-delta; eIF-3-delta {ECO:0000255; EIF3G; eIF3g {ECO:0000255; Eif3p42; EIF3-P42; eIF3-p44; EIF3S4; eukaryotic translation initiation factor 3 RNA-binding subunit; eukaryotic translation initiation factor 3 RNA-binding subunit {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 4; eukaryotic translation initiation factor 3 subunit 4 {ECO:0000255; eukaryotic translation initiation factor 3 subunit G; eukaryotic translation initiation factor 3 subunit G {ECO:0000255; eukaryotic translation initiation factor 3, subunit 4 (delta); eukaryotic translation initiation factor 3, subunit 4 (delta, 44 kDa); eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); eukaryotic translation initiation factor 3 subunit p42; eukaryotic translation initiation factor 3, subunit 4 delta; eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; eukaryotic translation initiation factor 3, subunit G; HAMAP-Rule:MF_03006}; p44; similar to eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa; translation initiation factor eIF3-p44; TU-189B2; Unknown (protein for MGC:128341); zgc:56553
Gene Symbols EIF3G
Host Species Rabbit
Immunogen A portion of amino acids 50-100 of human eIF3G.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8666
Target Species Human, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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