Invitrogen™ eIF3i Monoclonal Antibody (3B10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA520471

Catalog No. PIMA520471

Description

Peptide Sequence: FRTERPVNSA ALSPNYDHVV LGGGQEAMDV TTTSTRIGKF EARFFHLAFE EEFGRVKGHF GPINSVAFHP DGKSYSSGGE DGYVRIHYFD PQYFEFEFEA.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Specifications

• Antigen: eIF3i
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q13347
• Gene Symbols: Eif3i
• Immunogen: EIF3I (NP_003748.1, 226 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 3B10
• Conjugate: Unconjugated
• Gene: Eif3i
• Gene Alias: 36kDa; D4Ertd632e; eIF3 p36; eIF-3-beta; eIF3-beta; Eif3i; eIF3-p36; Eif3s2; Eukaryotic translation initiation factor 3 subunit 2; eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit I; predicted protein of HQ2242; PRO2242; subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP1; TRIP-1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8668
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid