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Invitrogen™ eIF3i Monoclonal Antibody (3B10)
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Catalog No. PIMA520471
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100 μg
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Catalog No. Quantity
PIMA520471 100 μg
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Catalog No. PIMA520471 Supplier Invitrogen™ Supplier No. MA520471
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Description

Mouse Monoclonal Antibody

Peptide Sequence: FRTERPVNSA ALSPNYDHVV LGGGQEAMDV TTTSTRIGKF EARFFHLAFE EEFGRVKGHF GPINSVAFHP DGKSYSSGGE DGYVRIHYFD PQYFEFEFEA.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF3i
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3B10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Eif3i
Gene Accession No. Q13347
Gene Alias 36kDa; D4Ertd632e; eIF3 p36; eIF-3-beta; eIF3-beta; Eif3i; eIF3-p36; Eif3s2; Eukaryotic translation initiation factor 3 subunit 2; eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit I; predicted protein of HQ2242; PRO2242; subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP1; TRIP-1
Gene Symbols Eif3i
Host Species Mouse
Immunogen EIF3I (NP_003748.1, 226 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8668
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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