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Tocris Bioscience™ eIF4A i28
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Catalog No. 781010 Shop All R&D Systems Products
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78-101-0 10 mg
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Catalog No. 78-101-0 Supplier Tocris Bioscience™ Supplier No. 7810/10
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Description

eIF4A inhibitor

eIF4A i28 is a eukaryotic initiation factor-4A (eIF4A) inhibitor (IC50 = 8.60 μM in an eIF4A ATPase assay). It decreases BJAB Burkitt lymphoma cell viability (EC50 = 0.46 μM in a CellTiter-Glo (CTG) luminescence cell viability assay. It acts as an RNA-competitive, ATP-uncompetitive eIF4A inhibitor.

Specifications

Chemical Name or Material 2-(5-(4-Butylphenyl)furan-2-yl)-6-nitroquinoline-4-carboxylic acid
CAS 2861994-92-3
Quantity 10 mg
Target DNA, RNA and Protein Synthesis Inhibitors
Molecular Formula C24H20N2O5
Purity 0.98
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