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Invitrogen™ eIF4A1 Polyclonal Antibody
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Catalog No. PIPA5115167
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PIPA5115167 100 μL
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Catalog No. PIPA5115167 Supplier Invitrogen™ Supplier No. PA5115167
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total EIF4A1.

eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre-initiation complex of ribosomes. Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates the genomic RNA synthesis of NS5B protein by unwinding the secondary structure of the HCV genome. It is ubiquitously expressed in most of normal tissues, but in variable amounts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF4A1
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene EIF4A1
Gene Accession No. P60842, P60843
Gene Alias ATP-dependent RNA helicase eIF4A-1; BM-010; DDX2A; Eif4; EIF4A; EIF-4A; Eif4a1; eIF-4A-I; eIF4A-I; eukaryotic initiation factor 4AI; Eukaryotic initiation factor 4A-I; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A1; initiation factor eIF-4A long form; QtsA-12280; unnamed protein product
Gene Symbols EIF4A1
Host Species Rabbit
Immunogen A synthesized peptide derived from human EIF4A1(Accession P60842), corresponding to amino acid residues V22-V72.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13681, 1973, 287436
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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