Invitrogen™ eIF4B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529540

Catalog No. PIPA529540

Description

Recommended positive controls: NT2D1, IMR32, MCF-7, U87-MG, SK-N-SH, SK-N-AS, 293T, A431, HeLa, HepG2, human EIF4B-transfected 293T. Predicted reactivity: Mouse (97%), Rat (97%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.

Specifications

• Antigen: eIF4B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Eif4b
• Gene Alias: 2310046H11Rik; AL024095; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; hypothetical protein; PRO1843
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1975, 75705
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.16 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P23588, Q8BGD9
• Gene Symbols: Eif4b
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 198 of Human EIF4B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG