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EIF4E Mouse anti-Human, Clone: OTI6C11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF502993

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.Specifications
EIF4E | |
Monoclonal | |
Unconjugated | |
EIF4E | |
AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E | |
Mouse | |
Affinity Chromatography | |
RUO | |
1977 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Flow Cytometry, Western Blot | |
OTI6C11 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P06730 | |
EIF4E | |
Full length human recombit protein of human EIF4E produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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