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EIF4E Mouse anti-Human, Clone: OTI6C11, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF502993

Encompass_Preferred

Catalog No. 50-166-1798


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.
Specifications

Specifications

EIF4E
Monoclonal
Unconjugated
EIF4E
AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E
Mouse
Affinity Chromatography
RUO
1977
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Flow Cytometry, Western Blot
OTI6C11
PBS with 8% trehalose and no preservative; pH 7.3
P06730
EIF4E
Full length human recombit protein of human EIF4E produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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